That is probably my favorite panel from Deadpool: Suicide Kings (it's from #4). Apologies for the glare in the center. I tried taking the picture 7 times, and that was the best result.
Carlos Barberi is definitely trying to ape (homage? copy?) Skottie Young's style, since Young was drawing that Marvelous Land of Oz mini-series at the time. That's fine with me, as I prefer Barberi trying his hand at being Skottie Young to Barberi's work in the rest of the mini-series. Which doesn't bode well for my satisfaction with the upcoming Deadpool #20. Then again, that issue is going to feature Deadpool and Spider-Man trying to stop Hit-Monkey. Considering my disinterest (or distaste) for most non-human primates in comics, that's possibly a bigger strike.
At the end of the previous issue, the Punisher performed and explosive headshot on Deadpool, and this is what he's dreaming about as his entire head regenerated. No, I'm not sure how, minus a brain, his body remained alive long enough to pull that off. What's a little creepy is he was trying to explain to Spider-Man he wasn't guilty of the particular crime he was being hunted for, and so Spidey and Daredevil (who showed up shortly after the unsafe cranial expansion) brought him in an empty apartment to pull himself together. Which suggests they watched his head grow back (well, Daredevil radar sensed it, but close enough*). even for two heroes who have been around the block as much as those two, you'd think that would freak them out more. They were pretty blase about it.
In the panel, we have Wade as Dorothy, Spidey as the Scarecrow, Frank as the Tin Man**, and Daredevil as the Cowardly Lion. Spidey as having no brain I get. He wouldn't believe 'Pool. Frank as having no heart, yeah, makes perfect sense. Daredevil lacking courage is a little dodgy, but this is Deadpool's regenerating brain we're talking about. It's close enough.
* Then again, he also heard and probably smelled it. That might be even worse than seeing it.
** Two panels from now he's going to kill the freak Deadpool mentions. Which is actually a munchkin, as the munchkin points out. Then Tin-Frank kills it.